Category: News

We highlight some of the many innovations showcased at the inaugural AACR Drug Discovery and Development (AACR D3) conference, including investigational KRAS degraders, approaches to drug p53 and MYC, and new AI tools for drug discovery.

The post AACR D3 Offered a Peek Into the Cancer Drug Pipeline, Innovative AI Tools, and More appeared first on American Association for Cancer Research (AACR).

The AACR D3 edition of “From the Bench” highlights cutting-edge approaches from the meeting that could shape the next generation of cancer treatments. We spoke with Andrea Wang-Gillam, MD, PhD, of Jacobio Pharmaceuticals; Kiyean Nam, PhD, of Qurient; Sharanya Nag, PhD, of Memorial Sloan Kettering Cancer Center; and Giuseppina Carbone, MD, about their innovative strategies to inhibit KRAS, enhance antibody-drug conjugate efficacy, and tackle resistance.

The post From the Bench, AACR D3 2026: Emerging Therapeutic Strategies to Inhibit KRAS, Enhance ADCs, and Tackle Resistance appeared first on American Association for Cancer Research (AACR).

With seven CAR T-cell therapies approved by the U.S. Food and Drug Administration, this innovative immunotherapy has revolutionized the treatment of blood cancers in recent years. Here, we provide an overview of how this therapy works and which cancers it’s approved to treat.

The post What Is CAR T-cell Therapy? appeared first on American Association for Cancer Research (AACR).

In July, the editors from AACR’s 10 peer-reviewed journals highlighted research on AI-driven molecular mapping of pancreatic cancer evolution, sex differences in immune responses, the discovery of a new subset of cells that promote brain metastasis, along with several other exciting articles.

The post Editors’ Picks, July 2026: AI-powered Pancreatic Proteomics, Sex-based Immune Differences, and More appeared first on American Association for Cancer Research (AACR).

The summer issue of Cancer Today includes articles about integrating patient-reported outcomes into clinical research and care, advances in preventing and treating graft-versus-host disease, researchers’ efforts to better understand the mechanisms of treatment resistance, advice about divulging a cancer diagnosis when dating, and more.

The post Cancer Today’s Summer 2026 Issue: Using Patient-reported Outcomes to Address Side Effects, Preventing Graft-versus-host Disease, and More appeared first on American Association for Cancer Research (AACR).

During the opening session of the AACR Conference on Drug Discovery and Development, the conference cochairs—Patricia M. LoRusso, DO, PhD (hc), FAACR; Keith T. Flaherty MD, FAACR; Lillian L. Siu, MD, FAACR; and Timothy A. Yap, MBBS, PhD—led a panel discussion with leading voices from industry and venture capital, including Alexis Borisy, MS, cofounder and chairman of the venture capital firm Curie.Bio; Chris Boshoff, MD, PhD, chief scientific officer and president of research and development at Pfizer; and David Schenkein, MD, general partner of the venture capital firm Google Ventures.

The post Inaugural AACR D3 Opens With Insights From Leaders Across Drug Discovery and Development appeared first on American Association for Cancer Research (AACR).

At the recent AACR Special Conference on Breaking Barriers in the Fight Against Rare Cancers, AACR Immediate Past President Lillian L. Siu, MD, FAACR, announced the AACR Rare Cancers Initiative. Learn more about how this new Initiative will marshal global resources and expertise to drive rare cancer research forward.

The post The AACR Rare Cancers Initiative: Uniting Researchers, Undoing Barriers, and Unleashing Progress appeared first on American Association for Cancer Research (AACR).

Cancer immunology expert and former AACR president Elizabeth Jaffee, MD, FAACR, discusses the latest progress in the research on pancreatic cancer vaccines and explains why cancer interception in individuals at high risk is the new frontier of the field.

The post From Treatment to Prevention: How Vaccines Are Reshaping the Fight Against Pancreatic Cancer appeared first on American Association for Cancer Research (AACR).

Exposure to wildfire smoke may increase the risk of developing several cancers, according to research presented at the AACR Annual Meeting 2026 by Shuguang Leng, MBBS, PhD, and Qizhen Wu, PhD, both of the University of New Mexico Comprehensive Cancer Center. Amid bigger U.S. wildfires, wildfire smoke’s impacts on human health are increasingly relevant.

The post Catching the Drift: How Wildfire Smoke Plumes May Increase Cancer Risk appeared first on American Association for Cancer Research (AACR).

Cancer researchers—including Elizabeth M. Jaffee, MD, FAACR, of the Sidney Kimmel Cancer Center at Johns Hopkins; Robert H. Vonderheide, MD, DPhil, FAACR, of the Abramson Cancer Center of the University of Pennsylvania; Kornelia Polyak, MD, PhD, FAACR, of Dana-Farber Cancer Institute and Harvard Medical School; Cornelia Ulrich, PhD, of the Huntsman Cancer Institute and University of Utah; Electra D. Paskett, PhD, FAACR, of The Ohio State University, and Anna Barker, PhD, FAACR, of the Ellison Medical Institute—explain how certain provisions of the White House Office of Management and Budget’s proposal to change how federal grants are awarded and managed would be harmful to U.S. scientific and medical innovation.

The post Cancer Researchers Explain How OMB’s Proposed Changes to Federal Grantmaking Will Cause Delays, Reduce Transparency, and Undermine Merit-based Processes appeared first on American Association for Cancer Research (AACR).