Genomics Reveal New Layers of Pediatric Leukemia Biology

During the opening plenary session of the AACR Special Conference in Cancer Research: Bridging Discovery and Clinical Impact in Pediatric Cancer, the keynote presenter, Charles Mullighan, MBBS (Hons), MSc, MD, and the 2025 AACR-St. Baldrick’s Foundation Pediatric Cancer Research Grantee, Nicole Michmerhuizen, PhD, spoke about pediatric leukemia research that is advancing our understanding of this devastating disease.
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Beyond Hangovers: Binge Drinking and the Risk of Early-onset Breast and Colorectal Cancers

Could higher rates of binge drinking be contributing to an increase in early-onset cancers? Mary Beth Terry, PhD, of Columbia University; Yin Cao, ScD, MPH, of Washington University School of Medicine in St. Louis; and Samantha Rees, PhD, MPH, of the BC Cancer Research Institute, spoke with Cancer Research Catalyst about how binge drinking impacts the body and their research into whether higher rates of binge drinking may be associated with the rise of breast and colorectal cancers in individuals under 50.
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Three Sisters, BRCA1 Mutations, and a Cancer Diagnosis While Pregnant

Carolyn Searles and her sisters all tested positive for a BRCA1 mutation and underwent double mastectomies to reduce their breast cancer risk. Still, Carolyn was diagnosed with breast cancer while 16 weeks pregnant. Last week, they joined a group of Pennsylvania constituents, which included AACR President-Elect Robert H. Vonderheide, MD, DPhil, FAACR, to advocate for NIH funding at the Rally for Medical Research. Learn more about Carolyn’s story and her experience at the Rally.
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AACR on Campus Poland/Ukraine: Creating New Opportunities for Cancer Care in Ukraine Amid War

Around a hundred early-career clinicians and researchers from Ukraine and Poland attended last month’s AACR on Campus event in Warsaw, held in partnership with the Maria Skłodowska-Curie National Research Institute of Oncology and the Global Medical Knowledge Alliance. At the event, Ukrainian oncologists shared how the war is impacting cancer care in their country and why events like this centered on international collaboration can help.
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AACR and Kids Beating Cancer Launch New Grant to Advance Pediatric Leukemia Research

AACR and Kids Beating Cancer have announced a new grant to support pediatric leukemia research, with a particular focus on high-risk acute myeloid leukemia subtypes at the AACR Special Conference in Cancer Research: Bridging Discovery and Clinical Impact in Pediatric Cancer. Through this partnership, the organizations aim to advance understanding of these aggressive diseases and accelerate the development of more effective treatments. AACR and Kids Beating Cancer leaders hope the grant will drive innovative discoveries that improve outcomes for children with cancer and their families.
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Party With a Purpose Honors the Power of Immunotherapy

This year’s Party with a Purpose, hosted by the Friends of the AACR Foundation, will honor Robert H. Vonderheide, MD, DPhil, FAACR, and Andrew Rech, MD, PhD, of the University of Pennsylvania, for their achievements and ongoing efforts to advance cancer immunotherapy research. Learn more about their mentor-mentee relationship and their current research.
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Shining a Light on Uterine Cancer: Rising Incidence and Mortality, Persistent Inequities

In contrast with many cancers, uterine cancer incidence and mortality are on the rise. The disease, which is a leading cause of death among gynecologic cancers in the United States, is also associated with deep racial disparities, disproportionately affecting Black women. Elizabeth M. Swisher, MD, the 2026-2028 Chair of the AACR Cancer Prevention Working Group (CPWG) steering committee, discussed risk factors, warning signs, and the urgent need for increased public awareness and research funding.
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Editors’ Picks, September 2026: Drug Resistance, Breast Cancer Treatment, COVID-19 and Cancer Care, and More

The September Editors’ Picks from AACR’s peer-reviewed journals include insights into cancer evolution in leukemia, a strategy for overcoming drug resistance, the impacts of the COVID-19 pandemic on cancer care, an investigational treatment for triple-negative breast cancer, and more.
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The Cancer Aftermath of the 9/11 Attacks on First Responders

In memory of those who lost their lives or families as a result of what happened on September 11, 2001, this edition of Cancer Research Catalyst reviews the effects of the attacks and showcases the new research being conducted in the 9/11-responder population.
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‘It Restored My Hope’: How the Margaret Foti Scholarship Helped Tsedey Tsegaye Reclaim Her Future

Tsedey Tsegaye had her sights on a career in health communication—until a civil war upended her life. A scholarship from AACR CEO Margaret Foti, through the Margaret Foti Foundation, gave her another chance to reclaim her dream and ultimately pursue a career that aims to make a meaningful contribution to cancer prevention, research, health communication, and cancer informatics.
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